Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats

Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats

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The current pilot study was conducted to compare the triple effect of garlic extract and metformin on hyperglycaemia, hypercholesterolaemia, and hypertriglyceridaemia in alloxan-induced type 1-like diabetic rats.Wistar rats were randomly divided into four groups.Control group included normal rats.

The second group included alloxan-induced type 1-like diabetic rats, receiving no treatment.The other two groups of diabetic rats were orange zinger tomato orally treated with 0.75 g of garlic extract per kg of body weight and 0.

05 of metformin g per kg of body weight respectively for four weeks.The pharmacological read more impact of garlic compounds on serum glucose and lipids as opposed to the glucose-lowering and lipid-lowering was highlighted in these experiments.These results revealed that garlic extract has a triple action on hyperglycaemia, hypertriglyceridemia, and hypercholesterolemia.

Its effect on hyperglycaemia is long lasting, and more pronounced compared to the metformin.Interestingly, it had a regulatory effect on glycaemia as highlighted in the control group.